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BDBM145279 US8952169, 58

SMILES: CNS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc3CCC(C)(C)Cc3c2)cc1F

InChI Key: InChIKey=IFZBXLWNXNDZMJ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145279   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145279
PNG
(US8952169, 58)
Show SMILES CNS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc3CCC(C)(C)Cc3c2)cc1F
Show InChI InChI=1S/C21H24ClFN2O4S/c1-21(2)7-6-13-4-5-16(8-14(13)11-21)29-12-15-9-19(23)17(10-18(15)22)20(26)25-30(27,28)24-3/h4-5,8-10,24H,6-7,11-12H2,1-3H3,(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 26n/an/an/an/a7.425



Xenon Pharmaceuticals Inc

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair