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BDBM145345 US8952169, 124

SMILES: CS(=O)(=O)NC(=O)c1cc(Cl)c(OC2CCCCC2)cc1F

InChI Key: InChIKey=JZKNVQGSRABGGX-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145345   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145345
PNG
(US8952169, 124)
Show SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(OC2CCCCC2)cc1F
Show InChI InChI=1S/C14H17ClFNO4S/c1-22(19,20)17-14(18)10-7-11(15)13(8-12(10)16)21-9-5-3-2-4-6-9/h7-9H,2-6H2,1H3,(H,17,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 738n/an/an/an/a7.425



Xenon Pharmaceuticals Inc

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair