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BDBM145450 US8952169, 229

SMILES: Fc1cc(OCC23CC4CC(CC(C4)C2)C3)c(cc1C(=O)NS(=O)(=O)N1CCC2(COC2)CC1)C1CC1

InChI Key: InChIKey=HZURPFKYJSCSOR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145450   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145450
PNG
(US8952169, 229)
Show SMILES Fc1cc(OCC23CC4CC(CC(C4)C2)C3)c(cc1C(=O)NS(=O)(=O)N1CCC2(COC2)CC1)C1CC1
Show InChI InChI=1S/C28H37FN2O5S/c29-24-11-25(36-17-28-12-18-7-19(13-28)9-20(8-18)14-28)22(21-1-2-21)10-23(24)26(32)30-37(33,34)31-5-3-27(4-6-31)15-35-16-27/h10-11,18-21H,1-9,12-17H2,(H,30,32)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 630n/an/an/an/a7.425



Xenon Pharmaceuticals Inc

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair