BindingDB logo
myBDB logout

BDBM145477 US8952169, 258

SMILES: Fc1cc(OCC2CC3CC3C2)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1

InChI Key: InChIKey=FWELSPUFIZEVIM-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145477   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145477
PNG
(US8952169, 258)
Show SMILES Fc1cc(OCC2CC3CC3C2)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1
Show InChI InChI=1/C20H24FNO4S/c21-18-9-19(26-10-11-5-13-7-14(13)6-11)16(12-1-2-12)8-17(18)20(23)22-27(24,25)15-3-4-15/h8-9,11-15H,1-7,10H2,(H,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 11n/an/an/an/a7.425



Xenon Pharmaceuticals Inc

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair