BDBM145888 US8957064, 25.0
SMILES Cc1cnc2nc(-c3ccc(CN4CC(C4)c4n[nH]c(n4)-c4cccc(C)n4)cc3)c(cn12)-c1ccccc1
InChI Key InChIKey=RYHINOVPVSNHAE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 145888
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 18nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair