BDBM145888 US8957064, 25.0

SMILES Cc1cnc2nc(-c3ccc(CN4CC(C4)c4n[nH]c(n4)-c4cccc(C)n4)cc3)c(cn12)-c1ccccc1

InChI Key InChIKey=RYHINOVPVSNHAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145888   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM145888(US8957064, 25.0)
Affinity DataIC50:  7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM145888(US8957064, 25.0)
Affinity DataIC50:  18nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails US Patent