BDBM146058 US8957068, 93
SMILES: CC(C)[C@H]1COC(=O)N1c1cc(C)nc(N[C@@H](C)c2ccccc2)n1
InChI Key: InChIKey=YURLMTCLTRJEOO-GOEBONIOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human)) | BDBM146058![]() (US8957068, 93) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 655 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc... | US Patent US8957068 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W28 | |||||||||||
More data for this Ligand-Target Pair |