BDBM146278 US8957068, 347::US8957068, 348

SMILES CC(C)[C@H]1COC(=O)N1c1ccnc(NC(C)c2nncn2C)n1

InChI Key InChIKey=UAOFIAZQHWNURC-RRKGBCIJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 146278   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM146278(US8957068, 347 | US8957068, 348)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM146278(US8957068, 347 | US8957068, 348)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In DepthDetails US Patent