BDBM14667 (3Z)-3-({4-[(dimethylamino)methyl]-5-methyl-3-(propan-2-yl)-1H-pyrrol-2-yl}methylidene)-6-(4-hydroxy-3-methoxyphenyl)-2,3-dihydro-1H-indol-2-one::indolinone analog 31
SMILES COc1cc(ccc1O)-c1ccc2\C(=C\c3[nH]c(C)c(CN(C)C)c3C(C)C)C(=O)Nc2c1
InChI Key InChIKey=OSFVSYFDKMYAJC-MOSHPQCFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 14667
Affinity DataIC50: 1.28E+3nMpH: 7.4 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...More data for this Ligand-Target Pair