BDBM147003 US8957074, 42

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)C(=O)N3C[C@H]4[C@H](N)[C@H]4C3)nc2n1C1CCCC1

InChI Key InChIKey=AKCQFRGYCUZLQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 147003   

TargetCyclin-dependent kinase 4(Human)
Novartis

US Patent
LigandPNGBDBM147003(US8957074, 42)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:An assay for monitoring CDK4/cyclin D1-catalyzed phosphorylation of pRb at the Ser780 site was performed using TR-FRET in a 384-well format, and was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM147003(US8957074, 42)
Affinity DataIC50: 1.50E+4nMT: 2°CAssay Description:A 384-well microtiter IMAP-FP (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent