BDBM14702 1,3-diethyl 2-[(1H-indazol-5-ylamino)methylidene]propanedioate::2-[(1H-Indazol-5-ylamino)-methylene]-malonic acid diethyl ester::bicyclic compound 7
SMILES CCOC(=O)C(C=Nc1ccc2n[nH]cc2c1)C(=O)OCC
InChI Key InChIKey=SKZMZIKAEKZBBB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 14702
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Leeds
University Of Leeds
Affinity DataKi: 3.20E+3nM ΔG°: -7.49kcal/mole IC50: 2.78E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Leeds
University Of Leeds
Affinity DataKi: 1.51E+4nM IC50: 1.23E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair