BDBM14717 1-(5-chloro 2,4-dimethoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea::3-(5-chloro-2,4-dimethoxyphenyl)-1-(5-cyanopyrazin-2-yl)urea::Urea Compound 2

SMILES: COc1cc(c(cc1NC(=O)Nc2cnc(cn2)C#N)Cl)OC

InChI Key: InChIKey=URQYPXQXSVUVRG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM14717 (3-(5-chloro-2,4-dimethoxyphenyl)-1-(5-cyanopyrazin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM14717 (3-(5-chloro-2,4-dimethoxyphenyl)-1-(5-cyanopyrazin...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair