BDBM14771 (E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylidene}amino carbamate::Filaminast::[1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino] carbamate

SMILES: COc1ccc(cc1OC1CCCC1)C(C)=NOC(N)=O

InChI Key: InChIKey=STTRYQAGHGJXJJ-UHFFFAOYSA-N

Data: 12 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 14771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	7.5	30
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cGMP-dependent 3',5'-cyclic phosphodiesterase [574-941] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+4	n/a	n/a	n/a	n/a	7.5	30
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [650-1084] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B [316-320,321-700,S319G,N320S,N321H,T322M] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D [372-376,381-715,S375G,I381V,S383G,G384S,V385H,K386M) (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-specific 3',5'-cyclic phosphodiesterase [531-875] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 7B [91-450] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [226-593] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [432-779] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1) 35-489] (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM14771 ((E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
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