BDBM14834 1-[5-(2-Hydroxy-1,1-dimethylethyl)-2-p-tolyl-2H-pyrazol-3-yl]-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea::3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB-796 Analog 11::CHEMBL107850::Dopamine D2 receptor and serotonin 2a receptor::diaryl urea compound 3

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)CO

InChI Key: InChIKey=GPWFFJYJAIOOMC-UHFFFAOYSA-N

Data: 3 Kd  2 K_off  1 K_on  1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM14834 (3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	36	n/a	n/a	n/a	7.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Mouse)	BDBM14834 (3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	56	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14834 (3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.000400	2.54E+4	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14834 (3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.000400	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14834 (3-[3-(1-hydroxy-2-methylpropan-2-yl)-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair