BDBM14837 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-naphthalen-1-ylurea::BIRB-796 Analog 4::CHEMBL420047::diaryl urea compound 6

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key: InChIKey=RHSMFYIHIIADSH-UHFFFAOYSA-N

Data: 1 IC50  4 Kd  2 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 14837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	7.0	23
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Mitogen-activated protein kinase 14 (Mouse)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.000120	1.13E+5	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.000120	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
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Discoidin domain-containing receptor 2 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Human)	BDBM14837 (BIRB-796 Analog 4 | 3-[3-tert-butyl-1-(4-methylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair