BDBM14839 1-(5-tert-Butyl-2-phenyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea::3-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB-796 Analog 33::CHEMBL318810::diaryl urea compound 8

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)n(n1)-c1ccccc1

InChI Key: InChIKey=IDTKLCNLVPKYPA-UHFFFAOYSA-N

Data: 4 Kd  2 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0900	n/a	n/a	n/a	7.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Mouse)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.230	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11/12/13/14 (Human)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0000150	1.54E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0970	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14839 (BIRB-796 Analog 33 | 3-(3-tert-butyl-1-phenyl-1H-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0000150	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair