BDBM14840 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-pyridin-4-yl-ethoxy)-naphthalen-1-yl]-urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(pyridin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB-796 Analog 30::diaryl urea compound 9

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCc2ccncc2)c2ccccc12)C(C)(C)C

InChI Key: InChIKey=RCOGIBMVENMBNJ-UHFFFAOYSA-N

Data: 3 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM14840 (BIRB-796 Analog 30 | 3-[3-tert-butyl-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.5	n/a	n/a	n/a	7.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Mouse)	BDBM14840 (BIRB-796 Analog 30 | 3-[3-tert-butyl-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Human)	BDBM14840 (BIRB-796 Analog 30 | 3-[3-tert-butyl-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase HCK (Human)	BDBM14840 (BIRB-796 Analog 30 | 3-[3-tert-butyl-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	901	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14840 (BIRB-796 Analog 30 | 3-[3-tert-butyl-1-(4-methylph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair