BDBM148985 US8962646, 7

SMILES CO[C@@]12CCC(=O)C[C@@]11CCN(C)[C@@H]2Cc2ccc(C(=O)NCCc3ccc(cc3)-c3c[nH]c(=O)[nH]c3=O)c(O)c12

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148985   

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  0.520nM ΔG°:  -12.7kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  42nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  860nM ΔG°:  -8.27kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent