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BDBM14934 2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-5-(5-cyano-2-methoxyphenyl)-4-hydroxyphenyl]butanedioic acid::5-amidino benzimidazole analog 45

SMILES: COc1ccc(cc1-c1cc(cc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O)C(CC(O)=O)C(O)=O)C#N

InChI Key: InChIKey=ZIPBJYAJKROKTE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14934   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor VII


(Homo sapiens (Human))
BDBM14934
PNG
(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-5-(...)
Show SMILES COc1ccc(cc1-c1cc(cc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O)C(CC(O)=O)C(O)=O)C#N
Show InChI InChI=1S/C26H21N5O6/c1-37-21-5-2-12(11-27)6-16(21)17-7-14(15(26(35)36)10-22(32)33)8-18(23(17)34)25-30-19-4-3-13(24(28)29)9-20(19)31-25/h2-9,15,34H,10H2,1H3,(H3,28,29)(H,30,31)(H,32,33)(H,35,36)
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Similars

Article
PubMed
280n/an/an/an/an/an/an/an/a



Celera



Assay Description
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...


Bioorg Med Chem Lett 16: 1596-600 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.040
BindingDB Entry DOI: 10.7270/Q2VX0DSZ
More data for this
Ligand-Target Pair