BDBM14949 2-aminoquinazoline 5::3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluoromethyl)phenyl]benzamide::CHEMBL385937::JMC511681 Compound 34

SMILES: Cc1ccc(cc1-c1ccc2nc(N)ncc2c1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=YEIASMOUYNOXGA-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 14949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck [245-498] (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM14949 (3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair