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BDBM150453 US10238633, Example 127::US8987249, 127::US9713606, 127

SMILES: O=C(NC(Cc1ccc2cn[nH]c2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2

InChI Key:

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 150453   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase I


(Homo sapiens (Human))
BDBM150453
PNG
(US10238633, Example 127 | US8987249, 127 | US97136...)
Show SMILES O=C(NC(Cc1ccc2cn[nH]c2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2
PDB

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UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...


US Patent US8987249 (2015)


BindingDB Entry DOI: 10.7270/Q2KP80WG
More data for this
Ligand-Target Pair
Dipeptidyl peptidase I


(Homo sapiens (Human))
BDBM150453
PNG
(US10238633, Example 127 | US8987249, 127 | US97136...)
Show SMILES O=C(NC(Cc1ccc2cn[nH]c2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...


US Patent US10238633 (2019)


BindingDB Entry DOI: 10.7270/Q22R3TZF
More data for this
Ligand-Target Pair
Dipeptidyl peptidase I


(Homo sapiens (Human))
BDBM150453
PNG
(US10238633, Example 127 | US8987249, 127 | US97136...)
Show SMILES O=C(NC(Cc1ccc2cn[nH]c2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/a6.025



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....


US Patent US9713606 (2017)


BindingDB Entry DOI: 10.7270/Q21G0P8M
More data for this
Ligand-Target Pair