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BDBM150768 2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(3-hydroxyphenyl)-ethanone (1)

SMILES: Oc1cccc(c1)C(=O)CSc1nnc2c(n1)[nH]c1ccccc21

InChI Key: InChIKey=JVXYSLOVQHIULD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150768   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM150768
PNG
(2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(3-h...)
Show SMILES Oc1cccc(c1)C(=O)CSc1nnc2c(n1)[nH]c1ccccc21
Show InChI InChI=1S/C17H12N4O2S/c22-11-5-3-4-10(8-11)14(23)9-24-17-19-16-15(20-21-17)12-6-1-2-7-13(12)18-16/h1-8,22H,9H2,(H,18,19,21)
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Similars

Article
PubMed
n/an/a 2.46E+3n/an/an/an/an/a310.15



Hazara University



Assay Description
Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat...


Bioorg Chem 58: 81-7 (2015)

More data for this
Ligand-Target Pair