BDBM15094 (2R)-4-{6-chloro-5-[(E)-2-(pyridin-4-yl)ethenyl]pyridin-3-yl}-1-(1H-indol-3-yl)butan-2-amine::trans-bispyridinylethylene analog 15

SMILES N[C@H](CCc1cnc(Cl)c(\C=C\c2ccncc2)c1)Cc1c[nH]c2ccccc12

InChI Key InChIKey=CFYHQUNHGODMIT-GZNAHNRGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15094   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM15094((2R)-4-{6-chloro-5-[(E)-2-(pyridin-4-yl)ethenyl]py...)
Affinity DataIC50:  198nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM15094((2R)-4-{6-chloro-5-[(E)-2-(pyridin-4-yl)ethenyl]py...)
Affinity DataIC50:  198nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed