BDBM151093 US8987273, 4-0

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc2cc(-c3ccccc3)c(nn12)-c1ccc(cc1)C1(N)CCC1

InChI Key InChIKey=ZPRYORAWHROYRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151093   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM151093(US8987273, 4-0)
Affinity DataIC50:  278nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM151093(US8987273, 4-0)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails US Patent