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BDBM151304 US8987314, B102

SMILES: NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)N1CCOCC1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=SDOSETWDOLQLRT-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151304   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151304
PNG
(US8987314, B102)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)N1CCOCC1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C29H30N4O7S3/c30-43(38,39)17-12-31-27(34)26(42(36,37)19-20-4-2-1-3-5-20)28-32-24-11-10-23(18-25(24)41-28)21-6-8-22(9-7-21)29(35)33-13-15-40-16-14-33/h1-11,18,26H,12-17,19H2,(H,31,34)(H2,30,38,39)
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5.29E+3n/an/an/an/a8.025



Bristol-Myers Squibb Co.

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM151304
PNG
(US8987314, B102)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)N1CCOCC1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C29H30N4O7S3/c30-43(38,39)17-12-31-27(34)26(42(36,37)19-20-4-2-1-3-5-20)28-32-24-11-10-23(18-25(24)41-28)21-6-8-22(9-7-21)29(35)33-13-15-40-16-14-33/h1-11,18,26H,12-17,19H2,(H,31,34)(H2,30,38,39)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 18n/an/an/an/a8.025



Bristol-Myers Squibb Co.

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair