BDBM15138 5-indazolyl pyridine 11g::5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-yl}-3-methyl-1H-indazole::A-674563::Biochemistry 469551 Compound 11::indazole-pyridine, 7

SMILES: Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

InChI Key: InChIKey=BPNUQXPIQBZCMR-UHFFFAOYSA-N

Data: 6 KI  7 IC50  442 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 461 hits for monomerid = 15138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	22
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cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	22
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit beta (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 11A (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase BRSK1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-6 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 6 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase kinase 2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Protein kinase C eta type (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TNNI3K (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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SRSF protein kinase 2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase D2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Macrophage-stimulating protein receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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eIF-2-alpha kinase GCN2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Myosin-IIIb (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK gamma (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-2 (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15138 (Biochemistry 469551 Compound 11 | 5-indazolyl pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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