BDBM15211 CHEMBL104264::H-89::H89::HT-89 (H-89)::N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide::N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide

SMILES: c1cc2cnccc2c(c1)S(=O)(=O)NCCNC\C=C\c3ccc(cc3)Br

InChI Key: InChIKey=ZKZXNDJNWUTGDK-UHFFFAOYSA-N

Data: 15 KI  30 IC50  4 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 49 hits for monomerid = 15211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-5 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-gamma serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Rat)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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MO15-related protein kinase Pfmrk (malaria parasite P. falciparum)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glycogen synthase kinase-3 beta (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Mouse)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	23	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Mouse)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-gamma serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	662	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		48	-10.1	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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cAMP-dependent protein kinase catalytic subunit beta (Rat)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Rat)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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cGMP-dependent protein kinase 1 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		480	-8.76	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase 1 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase 3 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.83E+4	-6.30	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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Myosin light chain kinase, smooth muscle (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase, smooth muscle (Chicken)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase kinase 2 (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.97E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit beta (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.97E+4	-6.28	n/a	n/a	n/a	n/a	n/a	n/a	30
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Protein kinase C alpha type (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.17E+4	-6.24	n/a	n/a	n/a	n/a	n/a	n/a	30
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Casein kinase I isoform alpha (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.83E+4	-6.12	n/a	n/a	n/a	n/a	n/a	n/a	30
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Casein kinase I isoform alpha (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha (Human)	BDBM15211 (CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+5	-5.36	n/a	n/a	n/a	n/a	n/a	n/a	30
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