BDBM152280 US8993556, 3-{2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl}-N-(1-methylpiperidin-4-yl)isoxazole-5-carboxamide

SMILES CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(on2)C(=O)NC2CCN(C)CC2)cc1

InChI Key InChIKey=MQTFYLWEEARRGE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152280   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM152280(US8993556, 3-{2-[4-(Dimethylamino)phenoxy]-4,6-dih...)
Affinity DataKd:  0.0660nMpH: 7.6Assay Description:The evaluation of the binding affinity (KD) of the compounds of formula (I) to the HSP90 protein was done using Biacore T100.His-HSP90 N-term domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent