BDBM152285 US8993556, N-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-5-{2-[4-(dimethylamino)phenoxy]-4,6-dihydroxyphenyl}isoxazole-3-carboxamide

SMILES CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(CC2)C2CCC(F)(F)CC2)cc1

InChI Key InChIKey=ODKRYHBJLAURJA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152285   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM152285(US8993556, N-[1-(4,4-Difluorocyclohexyl)piperidin-...)
Affinity DataKd:  0.0570nMpH: 7.6Assay Description:The evaluation of the binding affinity (KD) of the compounds of formula (I) to the HSP90 protein was done using Biacore T100.His-HSP90 N-term domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent