BDBM15243 1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulfanyl]-7-(1,2,3,6-tetrahydropyridin-4-yl)-1H,2H,3H,4H-pyrido[3,2-d]pyrimidin-2-one::10-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)sulfanyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-5,8,10-triazabicyclo[4.4.0]deca-2,4,7,11-tetraen-9-one::pyridol-pyrimidine compound 4

SMILES: c1cc(c(c(c1)Cl)N2c3cc(c(nc3CNC2=O)Sc4ccc(cc4F)F)C5=CCNCC5)Cl

InChI Key: InChIKey=PZUXNWPJBLCJKB-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Mouse)	BDBM15243 (1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 [G110A] (Mouse)	BDBM15243 (1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	7.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 [G110D] (Mouse)	BDBM15243 (1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	7.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair