BDBM152712 4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amino}pyridin-3-yl)ethyl]pyridin-2-amine (14)::US10759791, Compound 5::US9951014, Name 14b::nNOS inhibitor, 2

SMILES: Cc1cc(nc(c1)N)CCc2cc(cnc2)N(C)CCNC

InChI Key: InChIKey=BAILAIZRWKFZJT-UHFFFAOYSA-N

Data: 18 KI  1 Kd

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 152712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase oxygenase (Bacillus subtilis (strain 168))	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.76E+4	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		17	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	37
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Nitric oxide synthase, endothelial (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N] (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		117	-9.83	n/a	n/a	n/a	n/a	n/a	7.4	37
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Nitric oxide synthase, brain [D597N] (Rat)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		139	-9.72	n/a	n/a	n/a	n/a	n/a	7.4	37
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Nitric oxide synthase, inducible (Mouse)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Mouse)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Bovine)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Human)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Bovine)	BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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