BDBM152720 N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phenyl]methoxy}methyl)pyrrolidin-3-yl]oxy}methyl)phenyl]-2H-1λ⁴-thiophene-2-carboximidamide (25)::US9242957, QJ-II-199

SMILES: [H]/N=C(/c1cccs1)\Nc2cccc(c2)COC[C@@H]3C[C@@H](CN3)OCc4cccc(c4)N/C(=N\[H])/c5cccs5

InChI Key: InChIKey=GPVRORSBZUBDJB-UHFFFAOYSA-N

Data: 6 KI  1 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 152720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase oxygenase (Bacillus subtilis (strain 168))	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		21.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Mouse)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Bovine)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM152720 (N-[3-({[(3S,5S)-5-({[3-(thiophene-2-imidamido)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair