BDBM15297 CHEMBL34431::Cilostamide::N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-butyramide::N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide

SMILES: CN(C1CCCCC1)C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1

InChI Key: InChIKey=UIAYVIIHMORPSJ-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 15297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112] (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	22
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112] (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphodiesterase (Trypanosoma cruzi)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	24
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	24
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cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent 3',5'-cyclic phosphodiesterase (Rat)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Rat)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B (Bovine)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69.1	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM15297 (N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.1	n/a	n/a	n/a	n/a	n/a	n/a
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