BDBM153281 1-Benzofuran-2-yl-3-(4,7-dimethoxy-naphthalen-1-yl)-propenone (2)

SMILES: COc1ccc2c(OC)ccc(\C=C\C(=O)c3cc4ccccc4o3)c2c1

InChI Key: InChIKey=ZZNLOWNLKLCDFQ-YRNVUSSQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Secretory phospholipase A2, group V (sPLA2-V) (Homo sapiens (Human))	BDBM153281 (1-Benzofuran-2-yl-3-(4,7-dimethoxy-naphthalen-1-yl...) Show SMILES COc1ccc2c(OC)ccc(\C=C\C(=O)c3cc4ccccc4o3)c2c1 Show InChI InChI=1S/C23H18O4/c1-25-17-9-10-18-19(14-17)15(8-12-22(18)26-2)7-11-20(24)23-13-16-5-3-4-6-21(16)27-23/h3-14H,1-2H3/b11-7+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	7.5	25
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz					Assay Description Briefly, sn-2ester bond of the substrate 1,2-bis(heptanoylthio)-glycerophosphocholine was hydrolyzed by PLA2-V followed by the exposure of free thiol...				Chem Biol Drug Des 85: 729-42 (2015) Article DOI: 10.1111/cbdd.12457 BindingDB Entry DOI: 10.7270/Q26W98TX
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM153281 (1-Benzofuran-2-yl-3-(4,7-dimethoxy-naphthalen-1-yl...) Show SMILES COc1ccc2c(OC)ccc(\C=C\C(=O)c3cc4ccccc4o3)c2c1 Show InChI InChI=1S/C23H18O4/c1-25-17-9-10-18-19(14-17)15(8-12-22(18)26-2)7-11-20(24)23-13-16-5-3-4-6-21(16)27-23/h3-14H,1-2H3/b11-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	8.0	25
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz					Assay Description 100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...				Chem Biol Drug Des 85: 729-42 (2015) Article DOI: 10.1111/cbdd.12457 BindingDB Entry DOI: 10.7270/Q26W98TX
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM153281 (1-Benzofuran-2-yl-3-(4,7-dimethoxy-naphthalen-1-yl...) Show SMILES COc1ccc2c(OC)ccc(\C=C\C(=O)c3cc4ccccc4o3)c2c1 Show InChI InChI=1S/C23H18O4/c1-25-17-9-10-18-19(14-17)15(8-12-22(18)26-2)7-11-20(24)23-13-16-5-3-4-6-21(16)27-23/h3-14H,1-2H3/b11-7+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	8.0	25
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz					Assay Description 100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...				Chem Biol Drug Des 85: 729-42 (2015) Article DOI: 10.1111/cbdd.12457 BindingDB Entry DOI: 10.7270/Q26W98TX
					More data for this Ligand-Target Pair