BDBM15363 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol::CCT018159 analog 2

SMILES Cc1[nH]nc(c1-c1ccc2OCCOc2c1)-c1ccc(O)cc1O

InChI Key InChIKey=SQSSUJCNDQSVLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15363   

TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM15363(4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1...)
Affinity DataIC50:  6.08E+4nMAssay Description:Inhibition of yeast Hsp90 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM15363(4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1...)
Affinity DataIC50:  4.73E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed