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BDBM153768 US8999981, A13::US8999981, A14

SMILES: CC1(C)N(Cc2c(NC(=O)c3ccc4ccccc4n3)n[nH]c12)C(=O)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1

InChI Key: InChIKey=OLNSPGVULRENNA-ZBXWWWQKNA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153768   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM153768
PNG
(US8999981, A13 | US8999981, A14)
Show SMILES CC1(C)N(Cc2c(NC(=O)c3ccc4ccccc4n3)n[nH]c12)C(=O)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1
Show InChI InChI=1/C32H35N7O2/c1-32(2)28-25(29(36-35-28)34-30(40)27-15-14-22-11-6-7-13-26(22)33-27)20-39(32)31(41)38-19-23-12-8-16-37(23)18-24(38)17-21-9-4-3-5-10-21/h3-7,9-11,13-15,23-24H,8,12,16-20H2,1-2H3,(H2,34,35,36,40)/t23-,24-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
16.1 -10.8n/an/an/an/an/a7.430



Pfizer Inc

US Patent


Assay Description
Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US8999981 (2015)


BindingDB Entry DOI: 10.7270/Q2RR1X0K
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM153768
PNG
(US8999981, A13 | US8999981, A14)
Show SMILES CC1(C)N(Cc2c(NC(=O)c3ccc4ccccc4n3)n[nH]c12)C(=O)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1
Show InChI InChI=1/C32H35N7O2/c1-32(2)28-25(29(36-35-28)34-30(40)27-15-14-22-11-6-7-13-26(22)33-27)20-39(32)31(41)38-19-23-12-8-16-37(23)18-24(38)17-21-9-4-3-5-10-21/h3-7,9-11,13-15,23-24H,8,12,16-20H2,1-2H3,(H2,34,35,36,40)/t23-,24-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
27.7 -10.5n/an/an/an/an/a7.430



Pfizer Inc

US Patent


Assay Description
Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US8999981 (2015)


BindingDB Entry DOI: 10.7270/Q2RR1X0K
More data for this
Ligand-Target Pair