BDBM153778 US8999981, A23::US8999981, A24

SMILES CC1(C)N(Cc2c(NC(=O)c3cccc(Cl)n3)n[nH]c12)C(=O)N1CCN2CCCC2C1

InChI Key InChIKey=FQFNUHQYNGQBNA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153778   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153778(US8999981, A23 | US8999981, A24)
Affinity DataKi:  42.9nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153778(US8999981, A23 | US8999981, A24)
Affinity DataKi:  55.9nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent