BDBM15384 8-(2,5-dimethoxybenzyl)-2-fluoro-9-pent-4-ynyl-9H-purin-6-amine::8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-9-(pent-4-yn-1-yl)-9H-purin-6-amine::CHEMBL326082::PUZ::Purine-Based Inhibitor 11

SMILES: COc1ccc(c(c1)Cc2nc3c(nc(nc3n2CCCC#C)F)N)OC

InChI Key: InChIKey=RMOYVWKKOKERSW-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent molecular chaperone HSP82 (Baker's yeast)	BDBM15384 (PUZ | 8-(2,5-dimethoxybenzyl)-2-fluoro-9-pent-4-yn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha/90-beta (Human)	BDBM15384 (PUZ | 8-(2,5-dimethoxybenzyl)-2-fluoro-9-pent-4-yn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair