BDBM153841 US8999981, A86

SMILES CCC1(C)N(Cc2c(NC(=O)c3ncc(F)cc3F)n[nH]c12)C(=O)C1C[C@@H]2CCCN2C[C@@H]1C

InChI Key InChIKey=RQAUDZGXNVMFPI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153841   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153841(US8999981, A86)
Affinity DataKi:  74.1nM ΔG°:  -9.88kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent