BDBM153849 US8999981, A124::US8999981, A137::US8999981, A94

SMILES C.COCCCN1CCN([C@@H](C)C1)C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C

InChI Key InChIKey=SRDPXMVCEWFQBD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153849   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153849(US8999981, A94 | US8999981, A137 | US8999981, A124)
Affinity DataKi:  19.5nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153849(US8999981, A94 | US8999981, A137 | US8999981, A124)
Affinity DataKi:  23.8nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153849(US8999981, A94 | US8999981, A137 | US8999981, A124)
Affinity DataKi:  143nM ΔG°:  -9.49kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent