BDBM154021 US9012443, 14 (isomer 1)::US9012443, 14 (isomer 2)::US9012443, 14 (mixture of isomers)

SMILES O=S(=O)(Nc1ncns1)c1ccc2c(cccc2c1)N1CCOC(C1)c1ccccc1

InChI Key InChIKey=PRMPMEPZCSZBOP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 154021   

LigandPNGBDBM154021(US9012443, 14 (isomer 2) | US9012443, 14 (mixture ...)
Affinity DataIC50: 300nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

LigandPNGBDBM154021(US9012443, 14 (isomer 2) | US9012443, 14 (mixture ...)
Affinity DataIC50: 520nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

LigandPNGBDBM154021(US9012443, 14 (isomer 2) | US9012443, 14 (mixture ...)
Affinity DataIC50: 1.80E+3nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

LigandPNGBDBM154021(US9012443, 14 (isomer 2) | US9012443, 14 (mixture ...)
Affinity DataIC50: 3.00E+4nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent