BDBM154106 US9012443, 113

SMILES Fc1cnc(NS(=O)(=O)c2ccc3c(cccc3c2)-c2ccc(cc2C2CCNCC2)C(F)(F)F)s1

InChI Key InChIKey=GWMGJBFIGORRDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154106   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM154106(US9012443, 113)
Affinity DataIC50:  118nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM154106(US9012443, 113)
Affinity DataIC50:  80nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In DepthDetails US Patent