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BDBM154184 US9012443, 193

SMILES: Clc1ccc(Oc2nccc3cc(ccc23)S(=O)(=O)Nc2ccncn2)cc1Cl

InChI Key: InChIKey=SWJGXXRAIWHUPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 154184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM154184
PNG
(US9012443, 193)
Show SMILES Clc1ccc(Oc2nccc3cc(ccc23)S(=O)(=O)Nc2ccncn2)cc1Cl
Show InChI InChI=1S/C19H12Cl2N4O3S/c20-16-4-1-13(10-17(16)21)28-19-15-3-2-14(9-12(15)5-8-23-19)29(26,27)25-18-6-7-22-11-24-18/h1-11H,(H,22,24,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.98E+3n/an/an/an/an/an/a



Amgen Inc

US Patent


Assay Description
293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...


US Patent US9012443 (2015)


BindingDB Entry DOI: 10.7270/Q2N0158J
More data for this
Ligand-Target Pair