BDBM154576 K03861 (1)

SMILES: CN1CCN(CC1)Cc2ccc(cc2C(F)(F)F)NC(=O)Nc3ccc(cc3)Oc4ccnc(n4)N

InChI Key: InChIKey=PWDLXPJQFNVTNL-UHFFFAOYSA-N

Data: 9 IC50  6 Kd  4 ITC

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 154576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	50	n/a	n/a	n/a	7.5	834.45
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Cyclin-dependent kinase 2 [C118L] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	18.6	n/a	n/a	n/a	7.5	834.45
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Cyclin-dependent kinase 2 [A144C] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15.4	n/a	n/a	n/a	7.5	834.45
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Cyclin-dependent kinase 2 [C118L,A144C] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.70	n/a	n/a	n/a	7.5	834.45
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Cyclin-dependent kinase 2 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [F80T] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [F80M] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [C118L] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [C118I] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [A144C] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [A144G] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 [C118L,A144C] (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	7.5	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 8 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM154576 (K03861 (1)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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