BDBM15458 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-2-methoxypyrimidine::4-[4-(4-fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]-2-methoxypyrimidine::CHEMBL95692::SB-242235::SB242235

SMILES: COc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1

InChI Key: InChIKey=PDTYLGXVBIWRIM-UHFFFAOYSA-N

Data: 1 KI  13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 15458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein beta-1 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM15458 (SB-242235 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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