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BDBM155047 US9000044, 66

SMILES: Cc1c(CC(O)=O)cc2ccc(Cl)cc2c1-c1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key: InChIKey=MNXWHJYNJMPNPX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155047   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM155047
PNG
(US9000044, 66)
Show SMILES Cc1c(CC(O)=O)cc2ccc(Cl)cc2c1-c1ccc(NC(=O)Nc2ccccc2)cc1
Show InChI InChI=1S/C26H21ClN2O3/c1-16-19(14-24(30)31)13-18-7-10-20(27)15-23(18)25(16)17-8-11-22(12-9-17)29-26(32)28-21-5-3-2-4-6-21/h2-13,15H,14H2,1H3,(H,30,31)(H2,28,29,32)
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PC sid
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Similars

US Patent
n/an/a 19n/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
A whole cell receptor binding assay using [3H]ramatroban as the competing radioactive ligand was employed to evaluate the compound binding activity t...


US Patent US9000044 (2015)


BindingDB Entry DOI: 10.7270/Q2319TM9
More data for this
Ligand-Target Pair