BDBM155425 US9006454, I48

SMILES Cc1cc(C(O)=O)c2nc([nH]c2c1)-c1c(F)cc(cc1F)-c1ccccc1

InChI Key InChIKey=UYFGVFCDGKOMIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155425   

LigandPNGBDBM155425(US9006454, I48)
Affinity DataIC50: 177nMpH: 8.0Assay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent