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BDBM155686 US9012651, 116

SMILES: CC(C)[C@@H](NCc1nc(ccc1F)-c1ccc(cc1)C(F)(F)F)C(N)=O

InChI Key: InChIKey=LHJHRTCFTVFGOF-MRXNPFEDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155686   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 3


(Homo sapiens (Human))
BDBM155686
PNG
(US9012651, 116)
Show SMILES CC(C)[C@@H](NCc1nc(ccc1F)-c1ccc(cc1)C(F)(F)F)C(N)=O
Show InChI InChI=1S/C18H19F4N3O/c1-10(2)16(17(23)26)24-9-15-13(19)7-8-14(25-15)11-3-5-12(6-4-11)18(20,21)22/h3-8,10,16,24H,9H2,1-2H3,(H2,23,26)/t16-/m1/s1
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Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...


US Patent US9012651 (2015)


BindingDB Entry DOI: 10.7270/Q2H41Q5Z
More data for this
Ligand-Target Pair