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BDBM156230 US9018234, A

SMILES: COc1ccc(cc1)C1=C([N+]#[C-])C(C(C#N)=C(C)N1)c1ccc2[nH]nc(C)c2c1

InChI Key: InChIKey=PCSMSISWQCWMFT-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156230   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM156230
PNG
(US9018234, A)
Show SMILES COc1ccc(cc1)C1=C([N+]#[C-])C(C(C#N)=C(C)N1)c1ccc2[nH]nc(C)c2c1
Show InChI InChI=1/C23H19N5O/c1-13-19(12-24)21(16-7-10-20-18(11-16)14(2)27-28-20)23(25-3)22(26-13)15-5-8-17(29-4)9-6-15/h5-11,21,26H,1-2,4H3,(H,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 25n/an/an/an/a7.025



Bayer Intellectual Property GmbH

US Patent


Assay Description
Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...


US Patent US9018234 (2015)


BindingDB Entry DOI: 10.7270/Q2028Q8M
More data for this
Ligand-Target Pair