BDBM13531 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190

SMILES: Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=QHKYPYXTTXKZST-UHFFFAOYSA-N

Data: 2 KI  10 IC50  377 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 389 hits for monomerid = 13531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	7.4	25
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Discoidin domain-containing receptor 2 [A642S] (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor [G719C] (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	910	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase 9 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	210	n/a	n/a	n/a	7.4	25
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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STE20-like serine/threonine-protein kinase (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 32B (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
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Citron Rho-interacting kinase (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform delta (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform epsilon (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor [1-999,L858R] (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+6	n/a	n/a	n/a	n/a	n/a
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Cyclin-G-associated kinase (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase NLK (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit beta (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 36 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK gamma (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK beta (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a
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Atypical kinase COQ8B, mitochondrial (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-1B (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-2B (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase FRK (Human)	BDBM13531 (4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a
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