BDBM157550 US9023865, 391

SMILES Cc1ccc2nc(CNC(=O)Nc3cc4[nH]nc(-c5ccnc(C)c5)c4cn3)cn2c1

InChI Key InChIKey=QJFVLBPYVKWDRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157550   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM157550(US9023865, 391)
Affinity DataIC50: 22.2nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent